Nature

DNA polymorphism and epigenetic marks modulate the affinity of a scaffold/matrix attachment region to the nuclear matrix

Mechanisms that regulate attachment of the scaffold/matrix attachment regions (S/MARs) to the nuclear matrix remain largely unknown. We have studied the effect of simple sequence length polymorphism ...
Indiatimes

Scientists from Pune university prepare genome map of Scaffold/Matrix Attachment Regions

A team of scientists from Savitribai Phule Pune University (SPPU) and other institutes have, for the first time been able to prepare a map of human ‘Scaffold/Matrix Attachment Regions (S/MARs)’ which ...
EurekAlert!

New gene delivery approach could allow long-term persistence in proliferating cells

New Rochelle, NY, Sept. 22, 2017 -- Researchers added a scaffold/matrix attachment region (S/MAR) to a conventional adeno-associated virus (AAV) vector used for gene transfer, and the modified vectors ...
News Medical

Novel approach facilitates long-term persistence of AAV vector genomes in proliferating cells

Researchers added a scaffold/matrix attachment region (S/MAR) to a conventional adeno-associated virus (AAV) vector used for gene transfer, and the modified vectors were able to establish colonies and ...